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Highly Sensitive Acetylcholine Analysis – Cholinesterase Inhibitor Free

Detection of acetylcholine (ACh) has historically been difficult for in-vivo monitoring via microdialysis because of the low levels present in the brain. Traditional solutions typically artificially modify the physiological conditions, which change the basal state and lead to confounding or misinterpreted results.

Reduce your chromatography noise and increase sensitivity two-fold by adopting our breakthrough technology and cholinesterase inhibitor free technique! 

  • No acetylcholinesterase inhibitor required for the medial prefrontal cortex.
  • The new improved enzymatic column provides increased sensitivity
  • The reproducible sensitivity level of 5 fmol 
  • 18 minute run time with an internal standard, 13 minutes without internal standard.
  • Also allows for the detection of Choline
acetylcholine app note

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