Congratulations! Teleopto contributed to a research published on Science.

Congratulations! Teleopto contributed to a research published on Science.

Dr. Miyamoto et al, showed that perceptual memory consolidation requires top-down cortico-cortical input during None-REM sleep with the use of Teleopto.

The group applied Teleopto to inhibit cortical neuron during sleep and demonstrated how NREM sleep consolidated memory.

This is another exciting moment for us as our products helped our customer’s research.

Top-down cortical input during NREM sleep consolidates perceptual memory.
D. Miyamoto et al, (2016), Science

New Microdialysis Fraction Collector, FC-90

New Microdialysis Fraction Collector, FC-90

We are pleased to announce the launch of a new Microdialysis Fraction Collector, Model FC-90, designed by Amuza.

The new FC-90 Microdialysis Fraction Collector saves lab space and your time when collecting microdialysis samples from multiple animals, up to 4 at once. The FC-90’s quiet operation and narrow footprint are ideal for small spaces. Programmed and controlled by Android™ devices via Bluetooth. Robustly designed for microdialysis.

 

The Android robot is reproduced or modified from work created and shared by Google and used according to terms described in the Creative Commons 3.0 Attribution License.

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New Investigator Program

New Investigator Program

New Program Provides 10% Discounts

Amuza’s New Investigator Program provides special discounts for a 6 month period after registration.

10% discounts are available on the following products:

  • HPLC equipment and supplies
  • Microdialysis parts and equipment
  • ENO Nitrite and Nitrate analysis equipment and supplies

Eligibility: New Investigators who are establishing their first laboratory or have received startup funds for their first laboratory will be eligible to register for six months. Investigators are also eligible to register for six months when they move their lab to a new location. Investigators can only register for the New Investigator/New Lab program once.

Conditions: Registration is required to receive this discount. This discount does not apply to labor, shipping, or extended warranties, and cannot be combined with other discounts. The discount will not apply retroactively to orders placed before registration. The New Investigator/New Lab program is currently limited to US customers only. For the customers outside the US, please contact us to find out if you can receive a similar program in your country. We, Amuza Inc reserve the right to change the conditions of this program including the termination of this program anytime.

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Two publications for Teleopto wireless optogenetics

Two publications for Teleopto wireless optogenetics

While still a very new technology, results have been published in Neuron and Molecular Brain showing Teleopto’s utility in experiments that would be difficult to perform with traditional tethered systems:

Manita, S., Suzuki, T., Homma, C., Matsumoto, T., Odagawa, M., Yamada, K., … & Murayama, M. (2015). A Top-Down Cortical Circuit for Accurate Sensory Perception.Neuron  2015 Jun 3;86(5):1304-16

Dr. Murayama’s group used Teleopto to provide bilateral illumination to the mouse somatosensory cortex during experiments in Y-mazes and place preference cages. This allowed them to suppress tactile sensory circuits (M2 to S1 axons), thus degrading accurate sensory perception of tactile surfaces.

Sato, M., Ito, M., Nagase, M., Sugimura, Y. K., Takahashi, Y., Watabe, A. M., & Kato, F. (2015). The lateral parabrachial nucleus is actively involved in the acquisition of fear memory in miceMolecular Brain, 2015 Mar 27;8:22

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Fast Microdialysis for Serotonin and Dopamine

Fast Microdialysis for Serotonin and Dopamine

Eicom can increase the throughput, sensitivity, and temporal resolution of your next microdialysis experiment. Fast microdialysis allows basal level monitoring of dopamine and serotonin in mice with 3 minute online HPLC analyses and 6 minute sampling times. These conditions allow a detection limit for serotonin of 0.8 fMol with an Eicom HTEC-500 HPLC.

Developed by neuroscientists Anne Andrews and Hongyan Yang at UCLA in conjunction with Eicom, this application makes full use of the short analysis time by staggering injections from two different animals onto one Eicom HTEC 500 HPLC-ECD equipped with a PP-ODS II separation column.

The 6 minute sample time has already proven useful in unmasking physiologically relevant changes in extracellular serotonin levels too fast to examine with standard 20-minute samples. Furthermore, online microdialysis allowed them to troubleshoot microdialysis sampling at the beginning of their experiments instead of after hours of collection.

Two Eicom EAS-20s autoinjectors are programmed to collect 6-minute samples from two animals and alternate making injections on the HPLC. This allows 2 complete runs, one from each animal, in each 6-minute chromatogram.

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