Wireless EEG & EMG Recording Device in Mice

Achieve high-quality EEG data with lighter weight, wireless telemetry technology – as little as 2 grams!

ELG-2 Datalogger – Wireless Telemetry System for Mice

Wirelessly recording EEG in freely moving animals has unlocked numerous possibilities of discoveries in sleep, seizure, and neurological disorder research studies, previously limited to tethered recording systems. The ELG-2 Datalogger (EEG dataLoGger-2) is a wireless telemetry device for in vivo recording of EEG (electroencephalogram – brain) and EMG (electromyogram – muscle) activity in swaying mice and rats.

Enhanced EEG Setup to Unlock Discoveries

High Quality, Artifact-Free Data

Well shielded headstage with an internal amplifier avoids the 60 Hz noise commonly picked up by other systems.

Minimal Effect on Mouse Behavior

Wireless, lightweight headstage is
well-tolerated by small animals to
perform normal tasks.

Reliable, Quick Start EEG Recording

Have confidence in recorded data via
easy-to-use, turn on and go recording.

Everything you need to get started with EEG and EMG

Logger (aka Electrode), Charger with Universal 5 pin connector, Small battery or Large battery (for mouse or rat studies), EEG screws (2), GND screw (1), EMG silver wires (2), Data Analysis software; MicroSD card (not included)

The rechargeable data loggers are as small as 2g, allowing mice to behave normally
during chronic recording sessions in any size cage or chamber.

Extended Battery Life for Less Disruptions

With up to 26-hour battery life for mice and 70 hours of battery life for rats, the ELG-2 Datalogger lets you handle the mouse less. Often battery changes can be done just once a day (or less with larger batteries designed for rats). Users have found it convenient to change the battery while changing the mouse cage bedding to minimize interruptions during the study. Compare that to tethered animals, where some institutions discourage long-term use.

Less frequent battery changes means your EEG data is less likely to be affected by disruptions, and you can get on with your research!

Types of Research Using Telemetric Studies in Mice and Rats

Sleep Research

Epilepsy Models

Migraine Studies

Neurological Disorders

(Huntington’s, Alzheimer’s, schizophrenia, etc.)

Research Animals in Epilepsy Models

Discovering new treatments for seizures/epilepsy depends on EEG research in animal studies. The ELG-2 Datalogger is highly sensitive to EEG signals, easily distinguishing seizures with high precision. This small, but robust EEG recording device is well-tolerated by mice and rats, making it a reliable method of functional brain mapping in rodents.

There is no other system which meets my requirements for wireless operation, channel count, and usability with mice.

Yet-to-be-published ELG-2 User

Simple Telemetric EEG & EMG Recording

Our intuitive wireless device provides simple EEG and EMG recording in a mouse or rat behavioral study. Have confidence that the ready-to-use device is recording high-quality data from the start of your experiment.

Records on microSD Card
Easy Use without Disturbing Animal
Just Turn On and Start Recording
Data Stored on Card
Plug and Play Software
Records on microSD Card
Easy Use without Disturbing Animal
Just Turn On and Start Recording
Data Stored on Card
Plug and Play Software

Starts recording right when you’re ready.

Data Analysis of EEG & EMG Recordings

Amuza’s ELG-2 Datalogger system comes with data analysis software that is intuitive and highly compatible. Simply insert the microSD card and the software enables a quick overview of the recorded data from your mouse telemetry or rat telemetry study. The software is also capable of filtering and simple (FFT-based) alpha, theta, delta power calculation, as well as creating hypnogram plots for sleep analysis.

Data Format of ELG-2 System – The data format of the ELG-2 Datalogger system for EEG & EMG recordings is simple binary and is compatible with Matlab, Octave, and other software compatible with binary reading. Matlab sample codes are included in the package. Data from Amuza’s EEG data analysis software can be exported to EDF or TXT without any dedicated reader or additional software.

This highly compatible telemetry setup with easy-to-use data analysis software makes it easy to incorporate the ELG-2 Datalogger system with your existing equipment setup.

Why is our EEG data analysis software free?
We consult with neuroscientists every day. We share success stories, product use tips, and demo data, collaborating on experiments that bring knowledge to the field of neuroscience. Amuza’s mission to ‘Unlock the Potential for Discovery’ is achieved through transparent partnership and understanding. In these collaborative settings, we understand the importance of sharing data amongst your research team, in your home office, or with your network of fellow researchers in the pursuit of scientific discovery. By using free software with unlimited access and zero licensing fees, we seek to support open knowledge in the field of neuroscience.

Sample of scored results of sleep analysis.

Challenges of Tethered EEG Systems

Every neuroscience researcher has seen the challenges presented when working with tethered research animals. From stress to boredom, escape attempts and wire gnawing, these behaviors resulting from wired experiments can all lead to artifacts and failed experiments.

Wireless neuroscience research solutions, such as the ELG-2 Datalogger for EEG and EMG recording and data analysis, help to eliminate the costly delays of breaking a tether.

Unfortunately, performing safe and prolonged EEG in rodents is complicated by a slew of challenges, the most notorious of which is disconnections of the EEG cable from the rodent’s head . . . due to the high mobility of the tethered rodents.

“Enhanced setup for wired continuous long-term EEG monitoring in juvenile and adult rats: application for epilepsy and other disorders.” Click for the article.

Medlej, Yasser et al.

A Good EEG Choice for Social Interactions

With the wireless ELG-2 Datalogger, the well-shielded headstage creates a low noise setting. This allows the device to work effectively in high-density housing environments – noise does not affect neighboring cages. The lightweight wireless device functions well in social housing as the mice can freely interact. High throughput, high success rates are obtained from recordings from the ELG-2 Datalogger electrodes.

ELG-2 Datalogger Specifications

ConfigurationWireless, no receivers or bases required.
Number of ChannelsUp to 7
Weight2 g – 5 g
(Half the weight of competitors’ EEG recording devices.)
System ComponentsLogger (Electrode)
Charger with Universal 5 pin connector
Small battery or Large battery
EEG screws (2)
GND screw (1)
EMG silver wires (2)
Data Analysis software
MicroSD card (not included)
Communication24/7 continuous EEG and EMG monitoring recorded to removable microSD card on the headstage. Simultaneous recording of brain and muscle activity in communication studies.
CompatibilityWireless telemetry device works in any cage, rack, or maze/environment – no faraday cage required.
Works well with mice, rats, NHPs, other small animals.
Universal connector – or customize to fit your electrodes.
Works with Amuza’s wireless optogenetics device and 3rd party optogenetics systems.
SoftwareSeamless sharing of data with free software that can be installed on multiple computers. The highly compatible binary data format of EEG/EMG analysis software.
CustomizableCustom electrodes available. Call (858) 225-6869 for details.

Comparison of Wireless vs. Tethered EEG Recording Equipment

The issues surrounding tethers have led to a shift to wireless EEG equipment. Wireless inductive telemeters addressed many of the problems of tethered systems, but bring with them other challenges.

Amuza’s ELG-2 Wireless DataloggerTethered EEG Equipment
BehaviorWireless allows for less restrictions in animal motion and behavior.Tethers alter the natural behavior of the animals affecting data.
ArtifactsPoor signal-to-noise ratios with cables that act as antennae, causing artifacts in data.
Faraday CagesNo need for Faraday cages, which become inconvenient with multiple animal studies.Often requires Faraday cage to limit noise from external sources.
ScalabilityInfinite. No radio transmitters for this system.
Implant SurgeryThe flexible design allows for simple (EEG electrode placement).Complex surgery with PCB-based electrodes.

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Publications

Narikiyo, K., Mizuguchi, R., Ajima, A., Shiozaki, M., Hamanaka, H., Johansen, J. P., … & Yoshihara, Y. (2020). The claustrum coordinates cortical slow-wave activity. Nature Neuroscience, 1-13. 

Our Customizable Wireless Neuroscience Solutions Meet
the Needs of Our Customers’ Unique Experiments.