HPLC-ECD Component System, 800 Series
(Formerly the 700 Series)Protect your electrochemical data from noise, drift, and system limitations
Electrochemical detection offers unmatched sensitivity for electroactive compounds — but it also exposes weaknesses in conventional HPLC setups. Flow pulsation, temperature instability, and incompatible materials can quietly degrade signal quality, reduce reproducibility, and put critical data at risk.
The Eicom HPLC-ECD Component System, 800 Series is designed to address these risks directly, giving researchers a stable, flexible platform for high-sensitivity electrochemical analysis.
Many laboratories encounter these issues when using electrochemical detection with conventional HPLC systems:
Baseline noise and drift caused by pump pulsation
Reduced sensitivity when ECDs are paired with non-optimized LC systems
Retention time variability due to insufficient temperature control
Limited flexibility in systems that cannot expand as methods evolve
These challenges increase troubleshooting time, consume valuable samples, and reduce confidence in analytical results.
The HPLC-ECD Component System, 800 Series
(formerly the 700 Series) is a modular platform engineered to provide stable, high-sensitivity electrochemical analysis while integrating cleanly with existing HPLC setups.
ECD-800 — ultra-high sensitivity electrochemical detection
EP-800 — pulse-free liquid delivery with integrated degassing
ATC-800 — temperature control for stable retention times and signal response
Outcome: cleaner baselines, more reproducible runs, and flexibility as methods evolve.
How each component reduces risk and improves results
Electrochemical Detector, ECD-800
(Formerly ECD-700)
Risk addressed: signal noise, electrode instability, limited detection flexibility
The ECD-800 Electrochemical Detector provides ultra-high sensitivity by combining a three-electrode potentiostat design with a shielded flow cell architecture. This minimizes electrical noise and stabilizes applied potential at the working electrode.
Key benefits include:
High-sensitivity amperometric DC detection
Support for amperometric or coulometric detection modes
Optional dual working electrode configurations
Compatibility with a wide range of electrode materials, including graphite composite, glassy carbon, platinum, gold, and silver
Easy access to electrodes for routine maintenance
The ECD-800 allows established electrochemical methods to be transferred confidently while supporting new application development.
Pump System, EP-800
(Formerly EP-700)
Risk addressed: baseline noise caused by flow pulsation and contamination
Electrochemical detection is highly sensitive to flow instability. The EP-800 Pump System is engineered specifically to reduce pulsation at the source, eliminating one of the most common causes of ECD noise.
Key benefits include:
Reciprocal dual-piston pump with self-learning pulsation control
No external pulse damper required
Built-in two-channel online degasser
Support for one or two pumps for isocratic, gradient, or parallel workflows
Inert, non-metallic wetted surfaces to reduce background current
The EP-800 delivers stable, pulse-free flow for consistent electrochemical detection across a wide range of applications.
Temperature Controller, ATC-800
(Formerly ATC-700)
Risk addressed: retention time drift and poor run-to-run reproducibility
Even small temperature fluctuations can affect retention time and detector response. The ATC-800 Temperature Controller stabilizes both HPLC columns and electrochemical flow cells to maintain consistent analytical conditions.
Key benefits include:
Active heating and cooling using a Peltier element
Precise temperature regulation for improved reproducibility
Capacity for two columns up to 25 cm
Direct integration with the ECD-800 shielding box for flow cell temperature control
By controlling temperature at critical points in the system, the ATC-800 helps ensure reliable, repeatable results.
A system that adapts as your research evolves
The 800 Series is modular by design. Laboratories can:
Start with a single component (e.g., ECD-800 only)
Add pumps, detectors, or temperature control as methods expand
Run parallel applications or gradient workflows
Integrate with existing HPLC systems
This flexibility reduces the risk of outgrowing your instrumentation and protects long-term investment.
Typical applications
The HPLC-ECD Component System, 800 Series is commonly used for:
Neurochemical and neurotransmitter analysis
Microdialysis (offline and online)
Trace electroactive compound detection
Method development requiring ultra-high sensitivity
Research workflows demanding low noise and high stability
Specifications
The 800 Series succeeds the proven 700 Series platform. Core performance specifications remain consistent, with updated model designations and standardized system integration.
ECD-800 | |
|---|---|
| Electrochemical Cell | Amperometric with 3 electrode DC potentiostat (standard); space for an optional second cell |
| Second Cell (Optional) | Coulometric or amperometric |
| Working Electrode | Graphite composite (standard), glassy carbon, pure graphite, platinum, gold, silver |
| Optional Dual Electrode | Glassy carbon, graphite composite (both due a shared reference) |
| Reference Electrode | Ag/AgCl |
| Counter Electrode | 316 stainless steel |
| Applied Voltage Range | -2000 mV to +2000 mV, 1 mV increments |
| Auto Zero Function | Between -1000 nA and +1000 nA; triggered by external input |
EP-800 PUMP UNIT | |
|---|---|
| Pressure Limit | 20 MPa |
| Setting Flow Rate | 1~3000μL/min |
| Stable Flow Pump | 100~2000μL/min |
| Liquid Contacting Surfaces | PEEK, Sapphire, Ruby, PTFE, PCTFE |
| Special Features | Gradient control built-in, input signal for start/stop |
| Built-in Degasser | 2 channels: 300 µL volume/ea, up to 3.0 mL/min |
ATC-800 | |
|---|---|
| Temperature Range | 15-55°C, 1°C increment, 20-45°C (recommended range) |
| Temperature Accuracy | +/-0.05°C |
The specifications are subject to change without notice.
Let’s Get Started!
If electrochemical detection is critical to your research, system design matters.
Our team can help you: Evaluate your current HPLC setup, identify potential sources of noise or instability,
configure the right combination of ECD-800, EP-800, and ATC-800 for your application