Eicom Microdialysis Probes
Advantages of Eicom Microdialysis Probes
Reliable. We have been manufacturing microdialysis probes for 20 years. We inspect all probes for functionality before shipping. Our team is in the U.S. to provide direct support. We have an integrated support/sales team so you can rely on our expertise. We are always just a call or email away.
Faster: We have a lot of inventory for immediate delivery at our San Diego Office and ship on the same day when we receive an order before 1 pm (Pacific time). Please contact us to check our inventory.
Affordable. We offer our probes at a competitive price. This improves your bottom line without compromising the quality of the microdialysis products.
Flexible. Custom size probes are available even for low-volume orders.
In Stock
Microdialysis Probes
Fast delivery!
<2 weeks for custom sizes
Chronic Microdialysis
Acute Microdialysis
MRI or PET Imaging
Peripheral Tissues
About Microdialysis Probes
A microdialysis probe has a semi-permeable membrane. Our probes have a 220 µm outer diameter. The probe inlet connects to a syringe pump, which continuously perfuses through the probe. As the perfusate travels through the probe, analytes cross the membrane and travel out the probe outlet into sample vials on a fraction collector or to a sample loop of an analytical system via a narrow tubing. This valuable tool enables the sampling of rather low molecular weight compounds from within the extracellular space of tissues.
In the particular case of the brain and spinal cord, neurotransmitters are released to the extracellular space. This measurement has more meaning as informational transmitting than total tissue content. The collected extracellular fluid is used to determine the chemical composition with sub-nanomolar sensitivity and detect small changes because of manipulation, or related to a physiological/behavioral change. The microdialysis implanted animals behave close to normal conditions.
Chronic Microdialysis
CX-I Series Probes – Brain Microdialysis
- Best for mice and short experiments.
- Probes snap into guide cannulae.
- Membrane material: artificial cellulose with a 50,000 Da MWCO*.
Other MWCO membranes are available by special order. - Membrane ID/OD: 200/220 µm.
- Using a harness system to prevent pulling out the probe is recommended.
*MWCO = Molecular Weight Cut Off
Guide Cannula CXG-X
- Shaft: 0.5 mm OD stainless steel.
- The length is designated by X.
- The cup thickness is 2.5 mm.
X is the length of the guide cannula. Available in X = 2, 4, 6, 8, 10, 12 mm.
Y is the length of the membrane. Available in Y = 0.5 to 10 mm, in increments of 0.5 mm.
For faster delivery, consider ordering X = 4, 8, 12 mm and Y = 1, 2, 3 mm.
Other custom lengths may be available. Please contact a sales representative for details.
| CX-I Series | |
|---|---|
| CX-I-X-0Y | Probe; 1 each |
| CXG-X | Guide cannulae; 3 pcs/pk |
| CXD-X | Dummy probes; 3 pcs/pk |
| CXSG-X | The stereotaxic adaptor of guide; 1 each |
| Sterile | Sterilized with ethylene monoxide gas before shipping |
FZ Series Probes – Brain Microdialysis
- Best for rats or long-term experiments.
- Secure attachment to the guide cannula with a threaded cap nut.
- Membrane material: Artificial cellulose with 50,000 Da MWCO.
- Membrane ID/OD: 200/220 µm.
- Available in custom lengths at no additional charge.
Inlet Tubing
Inner 0.04 mm ID PFS*
Outer 0.63 mm OD SUS**
Outlet Tubing
Inner 0.075 mm ID PFS
Outer 0.63 mm OD SUS
Shaft
0.37 mm OD SUS
Membrane
0.22 mm OD, 0.20 mm ID
Artificial Cellulose
*PFS Polyimide Fused Silica
**SUS Passivated Stainless Steel 316
Guide Cannula AG-X
- 0.5 mm OD stainless steel.
- Fuses to the skull with acrylic resin/dental cement.
Cap Nut AC-5
- 5 mm OD.
- It does not fuse with acrylic resin/dental cement.
X is the length of the guide cannula. Available in X = 2, 4, 6, 8, 10, 12 mm.
Y is the length of the membrane. Available in Y = 0.5 to 10 mm, in increments of 0.5 mm.
For faster delivery, consider ordering X = 4, 8, 12 mm and Y = 1, 2, 3 mm.
| FZ Series | |
|---|---|
| FZ-X-0Y | Probe; 1 each |
| AG-X | Guide cannulae; 3 pcs/pk |
| AD-X | Dummy probes; 3 pcs/pk |
| SAG-X | The stereotaxic adaptor of guide; 1 each |
| AC-5 | Cap nut; 3 pcs/pk |
| Sterile | Sterilized with ethylene monoxide gas before shipping |
| AMI-X | Injection cannulae; 3 pcs/pk (AZ without membrane) |
MI-FZ Series Probes – Microinjection + Microdialysis
The MI-FZ is the fully compatible successor to the MI-AZ. The MI-FZ and MI-AZ probes use the same membranes, microinjection cannulae, and accessories.
- Injection cannula (0.075/0.15 mm ID/OD) outside the membrane.
- Position of injection cannula tip specified by the customer. Standard is in the middle of the membrane because it works better to monitor the effect of injection than if positioned at the membrane tip.
- Guide cannula OD is 0.7 mm.
- Refer to the FZ probe for X and Y specifications.
- For injection cannula without microdialysis, please see the bottom of each table in previous sections.
Please specify probe dimensions upon ordering. All probes are tailor-made.
Please allow up to 3 weeks for delivery.
X for shaft length and Y for membrane length. X = 1 to 20 mm, Y = 0.5 to 4 mm.
| MI-FZ Series | |
|---|---|
| MI-FZ-X-0Y | Probe with microinjection cannula; 1 each |
| MI-AG-X | Guide cannulae for MI-FZ; 3 pcs/pk |
| MI-AD-X | Dummy probes for MI-AG; 3 pcs/pk |
| MI-SAG-X | The stereotaxic adaptor of the guide, MI-AG; 1 each |
| AC-5 | Cap nut; 3 pcs/pk |
| Sterile | Sterilized with ethylene monoxide gas before shipping |
Acute Microdialysis
DZ Series Probes – Extra Small Brain Probes
- Best for direct implantation without guide cannula.
- Smallest and least expensive probe.
- Great for mice.
- Membrane material: artificial cellulose with a 50,000 Da MWCO.
- Membrane ID/OD: 200/220 µm.
- Use probe holder ATH-02 for the implant.
- Order by specifying probe dimensions. X for shaft length and Y for membrane length.
- X = 0.5 to 10 mm, Y = 0.5 to 4 mm.
| DZ Probe | |
|---|---|
| DZ-X-0Y | Probe; 1 each |
| ATH-02 | Probe holder for DZ type |
MRI or PET Imaging
C-I Series – Non-Metal Microdialysis Probes and Guides
- Best for MRI and PET studies.
- FEP tubing used for inlet and outlet.
- Membrane material: artificial cellulose with a 50,000 Da MWCO.
- Membrane ID/OD: 200/220 µm.
- Guide cannula OD: 0.66 mm.
Please order by specifying probe dimensions. All custom made. Allow us 3 weeks for delivery.
X for shaft length and Y for membrane length. X = 1 to 20 mm; Y = 0.5 to 4 mm.
| C-I Series | |
|---|---|
| C-I-X-0Y | Probe; 1 each |
| CG-X (FS) | Guide cannulae; 3 pcs/pk |
| CD-X (FS) | Dummy probes; 3 pcs/pk |
| AC-5 | Cap nut; 3 pcs/pk |
Peripheral Tissues
OP – Linear Probe
- Best for skin and other organs.
- The needle is on one end for easy implantation.
- Membrane material: artificial cellulose with a 50,000 Da MWCO.
- Membrane ID/OD: 200/220 µm.
- 40 µm diameter platinum wire inside supports membrane.
- Flexible tubing is polyethylene (PE-10).
- Flexible tubing OD: 0.61 mm.
- Inlet and outlet OD: 0.33 mm (= 26 G needle).
Order by specifying probe dimensions. X for each side of PE-10 tubing length and Y for membrane length.
X = 50 to 200 mm, Y = 1 to 20 mm, OP-100-10 is the most popular size.
| OP Probe | |
|---|---|
| OP-X-0Y | Probe; 1 each |
TP – Flexible Concentric Probe
- Best for blood vessels, GI tract.
- Membrane material: artificial cellulose with a 50,000 Da MWCO.
- Membrane ID/OD: 200/220 µm.
- Flexible shaft is TFE (Teflon®).
- Flexible shaft OD: 0.6 mm.
- Inlet and outlet OD: 0.33 mm (= 26 G needle).
- 0.04 mm fused silica tubing inside to minimize dead volume.
Order by specifying probe dimensions. X for TFE tubing length and Y for membrane length.
X = 10 to 200 mm, Y = 1 to 20 mm, TP-100-10 is the most popular size.
| TP Probe | |
|---|---|
| TP-X-0Y | Flexible concentric probe; 1 each |
Featured Video
New to Eicom Products?
Call us for advice on which microdialysis probes to use, or try a starter kit.
Our starter kits provide you with microdialysis probes and accessories to see the quality of our products. Your research success is our top priority. Come see our probes, products, and expert support in action!
Note: the starter kits are available for new customers only.
- Best for rats or long-term experiments.
- Secure attachment to the guide cannula with a threaded cap nut.
- Membrane material: Artificial cellulose with 50,000 Da MWCO.
- Membrane ID/OD: 200/220 µm.
- Available in custom lengths at no additional charge.
Inlet Tubing
Inner 0.04 mm ID PFS*
Outer 0.63 mm OD SUS**
Outlet Tubing
Inner 0.075 mm ID PFS
Outer 0.63 mm OD SUS
Shaft
0.30 mm OD SUS
Membrane
0.22 mm OD, 0.20 mm ID
Artificial Cellulose
*PFS Polyimide Fused Silica
**SUS Passivated Stainless Steel 316
Guide Cannula AG-X
- 0.5 mm OD stainless steel.
- Fuses to the skull with acrylic resin/dental cement.
Cap Nut AC-5
- 5 mm OD.
- It does not fuse with acrylic resin/dental cement.
X is the length of the guide cannula. Available in X = 2, 4, 6, 8, 10, 12 mm.
Y is the length of the membrane. Available in Y = 0.5 to 10 mm, in increments of 0.5 mm.
For faster delivery, consider ordering X = 4, 8, 12 mm and Y = 1, 2, 3 mm.
AZ Series
| AZ-X-0Y | Probe; 1 each |
| AG-X | Guide cannulae; 3 pcs/pk |
| AD-X | Dummy probes; 3 pcs/pk |
| SAG-X | The stereotaxic adaptor of guide; 1 each |
| AC-5 | Cap nut; 3 pcs/pk |
| Sterile | Sterilized with ethylene monoxide gas before shipping |
| AMI-X | Injection cannulae; 3 pcs/pk (AZ without membrane) |
*The MI-AZ series has been discontinued. Please contact us for further questions*
- Injection cannula (0.075/0.15 mm ID/OD) outside the membrane.
- Position of injection cannula tip specified by the customer. Standard is in the middle of the membrane because it works better to monitor the effect of injection than if positioned at the membrane tip.
- Guide cannula OD is 0.7 mm.
- Refer to the AZ probe for X and Y specifications.
- For injection cannula without microdialysis, please see the bottom of each table in previous sections.
Please specify probe dimensions upon ordering. All probes are tailor-made.
Please allow up to 3 weeks for delivery.
X for shaft length and Y for membrane length. X = 1 to 20 mm, Y = 0.5 to 4 mm.
| MI-AZ Series | |
|---|---|
| MI-AZ-X-0Y | Probe with microinjection cannula; 1 each |
| MI-AG-X | Guide cannulae for MI-AZ; 3 pcs/pk |
| MI-AD-X | Dummy probes for MI-AG; 3 pcs/pk |
| MI-SAG-X | The stereotaxic adaptor of the guide, MI-AG; 1 each |
| AC-5 | Cap nut; 3 pcs/pk |
| Sterile | Sterilized with ethylene monoxide gas before shipping |
Let’s Get Started!
Virtual demos available.