News and Articles
Successful fiber photometry in mazes and other complex environments
Fiber photometry is most commonly used to monitor activity and chemical signaling at a specific location in the brains of freely moving animals.
5 Tips for Successful EEG and EMG Recording in Freely Moving Mice and Rats
Tethers are often the weak link in EEG experiments. In this article, we describe five tips on how to successfully record EEG and EMG in freely moving mice and rats.
2021 Optimizations to Wireless Fiber Photometry and Wireless Optogenetics Products, Based on Customer Feedback
In 2021, we made many new upgrades, options, and improvements for our wireless fiber photometry and wireless optogenetics products.
Very Fast CRISPR (vfCRISPR) synchronizes and improves the accuracy of CRISPR cleavage using 365 nm light as a trigger.
The system requires: a guide RNA (gRNA) to target a specific DNA sequence, and a CRISPR-associated endonuclease (Cas9 protein) to perform the actual cleavage.
Microdialysis vs fiber photometry for neurotransmitters
Microdialysis and fiber photometry provide different insights into neurotransmitter dynamics in vivo. Compare their strengths in quantitative measurement, temporal resolution, analyte coverage, targeting, and experimental workflow.
Modular Maze System, the Free Maze Setup
We show you how the Free Maze is quite easy to configure. The orientation and position can be easily changed to give you different designs.
Choosing biosensors for fiber photometry: A guide to GECIs, GEFIs, and neurotransmitter sensors
Choosing the right biosensor is a critical step in fiber photometry experiments. This guide compares calcium indicators, neurotransmitter sensors, and other fluorescent biosensors to help researchers select the best tool for their biological question.
O’Hara Behavioral Testing Equipment
Built out of a desire to help standardize behavioral neuroscience research. O’Hara began developing automated behavior tests in order to improve the reliability of behavioral data.
Simultaneous Analysis of Glutamate and GABA for Neuroscience Applications
In this video, we’ll show you how to detect and analyze Glutamate and GABA in brain tissue or microdialysis samples in just 12 minutes.
Fast analysis of acetylcholine for neuroscience applications
We show you how to detect and analyze acetylcholine in brain microdialysis samples in 18 minutes, with minimal or no need to add an acetylcholine esterase inhibitor or AEI.
Precise Touch Operant Training
What is unique about our chambers is that they contain infrared sensors located at the top of the touchscreen itself that improve the accuracy of touch responses from small rodents.
Benefits of using HPLC-ECD for Neurotransmitter Detection
For qualitative and quantitative analysis of neurotransmitters, we recommend high-performance liquid chromatography detected with an electrochemical detector, known as HPLC-ECD.