- 0.22 mm outer diameter of the membrane.
- 0.37 mm outer diameter of the shaft, which is the needle between body part and membrane.
- 0.63 mm outer diameter for the inlet and outlet needles. Works with most other brands of connectors.
- All Eicom products are for animal research only.
- Keep the probe away from physical shock.
- The Inlet needle is longer than the outlet needle.
- Dura must be broken before insertion into the brain.
- “-X” indicates guide cannula length and “-Y” indicates membrane length.
- We can also customize probe and membrane lengths. Please contact us for more information.
- Custom sizes of inlet and outlet tubing are available.
Advantages of Eicom Microdialysis Probes
Reliable. We have been manufacturing microdialysis probes for 20 years. We inspect all probes for functionality before shipping. Our team is in the U.S. to provide direct support. We have an integrated support/sales team so you can rely on our expertise. We are always just a call or email away.
Faster: We have a lot of inventory for immediate delivery at our San Diego Office and ship on the same day when we receive an order before 1 pm (Pacific time). Please contact us to check our inventory.
Affordable. We offer our probes at a competitive price. This improves your bottom line without compromising the quality of the microdialysis products.
Flexible. Custom size probes are available even for low-volume orders.
About Microdialysis Probes
A microdialysis probe has a semi-permeable membrane. Our probes have a 220 µm outer diameter. The probe inlet connects to a syringe pump, which continuously perfuses through the probe. As the perfusate travels through the probe, analytes cross the membrane and travel out the probe outlet into sample vials on a fraction collector or to a sample loop of an analytical system via narrow tubing. This valuable tool enables the sampling of relatively low molecular weight compounds from within the extracellular space of tissues.
In the particular case of the brain and spinal cord, neurotransmitters are released to the extracellular space. This measurement has more meaning as informational transmitting than total tissue content. The collected extracellular fluid is used to determine the chemical composition with sub-nanomolar sensitivity and detect small changes due to manipulation or a physiological/behavioral change. The microdialysis-implanted animals behave close to normal conditions.